Les origines du Sida

HIV-1 group M subtype B was the first HIV discovered and is the predominant variant of AIDS virus in most countries outside of sub-Saharan Africa. However, the circumstances of its origin and emergence remain unresolved. Here we propose a geographic sequence and time line for the origin of subtype B and the emergence of pandemic HIV/AIDS out of Africa. Using HIV-1 gene sequences recovered from archival samples from some of the earliest known Haitian AIDS patients, we find that subtype B likely moved from Africa to Haiti in or around 1966 (1962–1970) and then spread there for some years before successfully dispersing elsewhere. A "pandemic" clade, encompassing the vast majority of non-Haitian subtype B infections in the United States and elsewhere around the world, subsequently emerged after a single migration of the viru

Voir : http://www.pnas.org/cgi/content/abstract/0705329104v2?maxtoshow%3D%26HITS%3D10%26hits%3D10%26RESULTFORMAT%3D%26fulltext%3DMichael+Worobey+%26searchid%3D1%26FIRSTINDEX%3D0%26resourcetype%3DHWCIT

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